Pharmaceutical Freeze Dryer Lyophilizer

Vekuma’s FDLS freeze dryers are designed for industrial large production of a range of bio and pharmaceutical products. Typical applications include medical vaccines, antibiotics, serum, penicillin, hormones and reagents.

The FDLS freeze drying units are complete with a hydraulic stoppering system and flexible shelves for vials closing under vacuum environment. And these lyophilizers can be equipped with CIP and SIP system to satisfy commercial aseptic production needs.

  • Shelf Area: 1.08~40.5m2
  • Condenser Capacity: 10~400Kgs/24Hrs
  • Applications: Pharmaceutical, Vaccines, PCR Plates, ELISA Plates, Serum, Reagents etc.

Technical Specifications

Model FD-1LS FD-2LS FD-3LS FD-5LS
Shelf Area 1.08m2 2.16m2 3.24m2 5.25m2
Shelves No. 4+1 6+1 6+1 7+1
Shelves Size 600*450mm 600*600mm 600*900mm 750*1000mm
Shelves Temp. -55C~+70C -55C~+70C -55C~+70C -55C~+70C
Condenser 10Kgs/24Hrs 20Kgs/24Hrs 30Kgs/24Hrs 50Kgs/24Hrs
Condenser Temp. -85C -85C -85C -85C
Final Vacuum <1Pa <1Pa <1Pa <1Pa
Power Install 13.5Kw 18Kw 21Kw 28Kw
Size W*L*H 1200*2200*2300 1500*2350*2500 1500*2800*2500 1600*4000*2800
2R/4R 4144 8214 12432 19964
6R/8R 2160 4374 6480 10710
Model FD-10LS FD-20LS FD-30LS FD-40LS
Shelf Area 9.72m2 19.8m2 29.7m2 40.5m2
Shelves No. 9+1 11+1 11+1 15+1
Shelves Size 900*1200mm 1200*1500mm 1500*1800mm 1500*1800mm
Shelves Temp. -55C~+70C -55C~+70C -55C~+70C -55C~+70C
Condenser 100Kgs/24Hrs 200Kgs/24Hrs 300Kgs/24Hrs 400Kgs/24Hrs
Condenser Temp. -85C -85C -85C -85C
Final Vacuum <1Pa <1Pa <1Pa <1Pa
Power Install 60Kw 85Kw 98Kw 125Kw
Size W*L*H 1900*6000*3200 2200*7500*3600 2500*9000*3800 2500*9000*4000mm
2R/4R 37800 76725 114576 156240
6R/8R 19440 40392 60588 82620

Technical Details

Vekuma has been designed and manufactured production scale lyophilizers for the pharmaceutical and biotechnology industry. Which is carried out in accordance with the guidelines of GMP, FDA and CE. We support your drugs development from very beginning lab research development, to process optimization, pilot production and final success in commercial and industrial mass production. 

All FDLS pharmaceutical freeze dryers are modular engineered with standardized sub-systems that can be flexible configured as per user’s reqirement, such as CIP, SIP, redundant compressors, vacuum pumps and fluid pumps. Fit both aseptic and non-aseptic production.

  • S/S made, rectangular drying chamber, PUF insulation.
  • Rounded inner corners for easy cleaning.
  • Sloped chamber bottom for water easy draining.
  • Tempered glass observe window with illuminator.
  • Vacuum leakage <5Pa L/S.
  • Heavy-duty, hinged door.
  • Stainless steel material, PUF insulated.
  • D-form, lubricate free door gasket.
  • Door with sight glass.
  • Door position sensor.
  • Stainless steel shelves, both surfaces polish Ra<0.4um.
  • Sandwich type shelves.
  • Silicone oil based, temperature controlled shelves can be heated and cooled.
  • Temperature difference between shelves and plate points <+/-1C.
  • Hydraulic stoppering device for shelves move up or down for vials closing under vacuum.
  • 2-chambers system with external ice condenser.
  • Stainless steel ice condenser.
  • Isolate valve between drying chamber and ice condenser.
  • Coils surface 1:1 with shelf area.
  • Sloped bottom for water easy draining.
  • Hot water or steam defrost.
  • 2-stage oil sealed rotary vane vacuum pump.
  • Roots pump for larger models.
  • Vacuum pump isolation valve.
  • Stainless steel vacuum pipe and bellows.
  • 2-stage semi-hermetic compressor.
  • Water cooling method.
  • Cool shelves through plate heat exchanger.
  • Cool ice condenser by refrigerant direct expands.
  • Centrifugal pump.
  • Electric heating, PID control.
  • Stainless steel fluid pipe with insulation.
  • PLC and touch screen HMI based control system.
  • LYO-MEGA interface.
  • PC control software.
  • SCADA package.
  • UPS module.
  • Clean in place system.
  • Sterilize in place system.
  • Pirani vacuum gauge.
  • Capacitive vacuum gauge.
  • PT-100 temperature sensors.
  • Pneumatically operated air&water isolate valves.
  • IQ, OPQ.
  • FAT, SAT.
  • Qualification files.

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